Host Defense Reishi Extract supports heart and immune health with mushroom mycelium. Reishi helps support cardiovascular function energy stamina and a healthy immune response. Known as the Mushroom of Immortality it has a long history of traditional use for whole body wellness and also supports a calm and relaxed body and mind. Suggested use is one full dropper twice daily with food or on an empty stomach or as directed by a healthcare advisor. Host Defense products contain no fillers and are third party tested for quality and safety. Made by Fungi Perfecti a family owned company founded in 1980 by Paul Stamets this supplement is grown in Washington State using cultivated mushroom mycelium and fruit bodies.